2. Signaling Pathways
  3. Anti-infection
  4. Parasite

Parasite

Parasite

Related Products

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Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.

Parasite Isoform Specific Products:

Parasite Isoform Comparison
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-161171
    Antimalarial agent 37
    		Inhibitor
    Antimalarial agent 37 (compound 33) is a selective inhibitor against Type Ⅱ kinase with antiplasmodial activity. Antimalarial agent 37 exhibited cytotoxicity and selectivity towards cancer cells HepG2 and MCF 7.
    Antimalarial agent 37
  • HY-136438R
    Toltrazuril sulfoxide (Standard)
    		Inhibitor
    Toltrazuril sulfoxide (Standard) is the analytical standard of Toltrazuril sulfoxide. This product is intended for research and analytical applications. Toltrazuril sulfoxide is a short-lived intermediary metabolite of Toltrazuril (HY-B0175), and then can be metabolized to the reactive toltrazuril sulfone (TZR-SO2) in vivo. Toltrazuril is an antiprotozoal agent that acts upon Coccidia parasites.
    Toltrazuril sulfoxide (Standard)
  • HY-151942
    Antitrypanosomal agent 10
    		Inhibitor
    Antitrypanosomal agent 10 is an antitrypanosomal agent that inhibits Trypanosoma cruzi with an IC50 of 0.28 μM.
    Antitrypanosomal agent 10
  • HY-N5109
    Cheilanthifoline
    		Inhibitor
    Cheilanthifoline, an alkaloid, is isolated from Corydalis calliantha. Cheilanthifoline exhibits antiplasmodial activities against Plasmodium falciparum, with IC50s of 0.90 μg/mL and 1.22 μg/mL for wild type (TM4) and multidrug resistant (K1) strains, respectively.
    Cheilanthifoline
  • HY-127160R
    Benzoxonium chloride (Standard)
    		Inhibitor
    Benzoxonium (chloride) (Standard) is the analytical standard of Benzoxonium (chloride). This product is intended for research and analytical applications. Benzoxonium chloride is an anti-leishmanial agent. Benzoxonium chloride inhibits bacteria, certain protozoa, yeasts and non-spore forming organisms.
    Benzoxonium chloride (Standard)
  • HY-162905
    Antimalarial agent 43
    		Inhibitor
    Antimalarial agent 43 (compound 16c) is an antimalarial compound, with an IC50 value of 0.0151 μM against 3D7 strain.
    Antimalarial agent 43
  • HY-162290
    Z2206320703
    Z2206320703 is a potential lead candidate compound against IspC.
    Z2206320703
  • HY-P990214
    Anti-Mouse IL-3 Antibody (MP2-8F8)
    		Inhibitor
    Anti-Mouse IL-3 Antibody (MP2-8F8) is an anti-mouse IL-3 IgG1 monoclonal antibody. Anti-Mouse IL-3 Antibody (MP2-8F8) relieves joint inflammation by reducing synovial leukocyte infiltration and cytokine levels. Anti-Mouse IL-3 Antibody (MP2-8F8) can reduce the accumulation of basophils. Anti-Mouse IL-3 Antibody (MP2-8F8) can be used for researches on inflammation or infection conditions such as arthritis and parasitic infections.
    Anti-Mouse IL-3 Antibody (MP2-8F8)
  • HY-151574
    PfGSK3/PfPK6-IN-1
    		Inhibitor
    PfGSK3/PfPK6-IN-1 (compound 23e) is a potent inhibitor of plasmodial kinases PfGSK3 and PfPK6, with IC50s of 97 nM and 8 nM, respectively. PfGSK3/PfPK6-IN-1 exerts antiplasmodial activity against blood stage Pf3D7 parasites with an EC50 value of 1.4 mM.
    PfGSK3/PfPK6-IN-1
  • HY-N10441
    3β-Hydroxy-hop-22(29)-ene
    		Inhibitor
    3β-Hydroxy-hop-22(29)-ene (compound 3) is a potent antiparasitic agent. 3β-Hydroxy-hop-22(29)-ene shows moderate activity against Trypanosoma cruzi and Leishmania mexicana.
    3β-Hydroxy-hop-22(29)-ene
  • HY-135562
    Ascofuranone
    		Inhibitor
    Ascofuranone, a prenylphenol antibiotic, is a potent and selective trypanosome alternative oxidase (TAO) inhibitor. Ascofuranone has inhibitory activity against human dihydroorotate dehydrogenase (DHODH). Ascofuranone has diverse physiological activities, including antibiotic, hypolipidemic, anti-inflammatory, and anti-cancer.
    Ascofuranone
  • HY-N0193S1
    Artesunate-d4
    		Inhibitor
    Artesunate-d4 is deuterium labeled Artesunate. Artesunate is an inhibitor of both STAT-3 and exported protein 1 (EXP1).
    Artesunate-d<sub>4</sub>
  • HY-N0498R
    Nitidine chloride (Standard)
    		Inhibitor
    Nitidine (chloride) (Standard) is the analytical standard of Nitidine (chloride). This product is intended for research and analytical applications. Nitidine chloride, a potential anti-malarial lead compound derived from Zanthoxylum nitidum (Roxb) DC, exerts potent anticancer activity through diverse pathways, including inducing apoptosis, inhibiting STAT3 signaling cascade, DNA topoisomerase 1 and 2A, ERK and c-Src/FAK associated signaling pathway. Nitidine chloride inhibits LPS-induced inflammatory cytokines production via MAPK and NF-kB pathway.
    Nitidine chloride (Standard)
  • HY-172523
    CDA-IN-3
    		Inhibitor
    CDA-IN-3 (NCDI) is an inhibitor of chitin deacetylase (CDA) with anti-parasitic activity. CDA-IN-3 disrupts the chitin metabolism of nematodes, leading to an increase in the level of ROS in nematodes and causing cell damage. CDA-IN-3 has a significant inhibitory effect on all developmental stages of Caenorhabditis elegans. CDA-IN-3 can be used in the research of the anti-infection field .
    CDA-IN-3
  • HY-B0688S1
    Dapsone-d4
    		Inhibitor
    Dapsone-d4 is the deuterium labeled Dapsone. Dapsone (4,4′-Diaminodiphenyl sulfone) is an orally active and blood-brain penetrant sulfonamide antibiotic with bacteriostatic, antimycobacterial and antiprotozoal activities. Dapsone?exerts effective antileprosy activity?and inhibits folate synthesis in cell extracts of?M. leprae. Dapsone is used for dermatologic disorder research, including leprosy, dermatitis herpetiformis, acne vulgaris et al.
    Dapsone-d<sub>4</sub>
  • HY-145327
    Antimalarial agent 7
    Antimalarial agent 7 is a potent inhibitor of PfATP4. PfATP4 is an essential ion pump on the parasite surface. Antimalarial agent 7 has the potential for the research of human malaria parasite, Plasmodium falciparum.
    Antimalarial agent 7
  • HY-178784
    Antileishmanial agent-37
    		Inhibitor
    Antileishmanial agent-37 (Compound 1b) is an antileishmanial agent, TbPTR1 (an IC50 value of 17.1 μM) and LmPTR1 inhibitor. Anti-leishmaniasis agent-37 has a moderate effect against Leishmania infantum.
    Antileishmanial agent-37
  • HY-121405
    Malonomicin
    		Inhibitor
    Malonomicin (Antibiotic K16) is an antibiotic with anti-protozoa and anti-trypanosome activities. Malonomicin also shows anti-trypanosome activity in vivo.
    Malonomicin
  • HY-101725A
    (R)-Meclonazepam
    		Inhibitor
    (R)-Meclonazepam (Ro 11-3624) is an inactive enantiomer of Meclonazepam. Meclonazepam is a benzodiazepine derivative with anti-schistosomiasis activities.
    (R)-Meclonazepam
  • HY-N10900
    Bruceine C
    		Inhibitor
    Bruceine C, a quassinoid, is a nature product that could be isolated from fruits of Br. jaVanica. Bruceine C has anti-Babesial activity.
    Bruceine C
Parasite Isoform Comparison

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